Instinct Written in Code AI has become one of the most overused terms in laboratory medicine today. In pathology, immunohistochemistry, and cytology, we hear it almost everywhere — in microscopes, scanners, stainers, software, and sometimes even in places where it has very little to do with actual “intelligence.” And yet… AI can truly be a very effective tool. But only under one condition: if we understand what it really is. Not a Thinking Mind — but Instinct. Artificial intelligence in...

Why “home-made” IHC controls are a bad idea — and how standardized materials save diagnostics. In immunohistochemistry, every error can have real clinical consequences. No surprise there: IHC determines treatment, eligibility for targeted therapies, tumor diagnostics, and even risk assessment. And yet, in many laboratories, in-house controls still reign — cut from patient blocks, assembled into tissue arrays, or “put together” from whatever happens to be available. Nobody pays attention to...

PRAME (QR005) (PReferentially expressed Antigen in MElanoma) by Quartett GmbH is a tumor associated antigen that is preferentially...